Distribution of HLA Class II Antigens in Three North Indian Populations
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THE DISTRIBUTION OF CLASS I HLA ANTIGENS IN 1000 NORMAL INDIVIDUALS IN KHORASAN PROVINCE
In this paper, the antigen and gene frequencies of class I HLA antigens were evaluated in 1000 individuals in Khorasan province in northeast Iran, and compared with statistics of other countries. The results and a general discussion are presented.
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Background: The high polymorphism in the human leukocyte antigen (HLA) genes can be used as an identity of individuals to compare with other populations. This extreme polymorphism in the HLA system is accountable for the differences in alleles and haplotypes among ethnic groups, populations, and the inhabitants of many regions. Objective: To define the frequency of HLA alleles and haplotypes am...
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Ulcerative colitis (UC) is a nonspecific acute and chronic inflammatory bowel disease that diffusely involves the colonic mucosa. The etiology of UC has not yet been elucidated fully. However, many studies have found that immunologic disorders may play a role in the pathogenesis of UC. In addition, due to an increased frequency of UC in families, especially an increased monozygotic compared...
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in this paper, the antigen and gene frequencies of class i hla antigens were evaluated in 1000 individuals in khorasan province in northeast iran, and compared with statistics of other countries. the results and a general discussion are presented.
متن کاملAssociation between HLA-Class I and HLA-Class II Alleles and Mycobacterium Tuberculosis Infection in Iraqi Patients from Baghdad City
Background: Pulmonary tuberculosis (PT) is one of the endemic diseases in Iraq, and among the suggested predisposing factors are alleles of the human leukocyte antigen (HLA) system. We sought to investigate the association between HLA-class I (A and B) and -class II (DR and DQ) alleles in a sample of PT Iraqi patients.Methods: lymphocytes of 105 PT patients and 40 controls were phenotyped for H...
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ژورنال
عنوان ژورنال: INTERNATIONAL JOURNAL OF HUMAN GENETICS
سال: 2001
ISSN: 0972-3757,2456-6330
DOI: 10.31901/24566330.2001/01.04.08